France: B.1.640 declared a VOI after more than 500 cases found

Sars-CoV-2 variant B.1.640 has been reclassified as a Variant of Interest in France after a new risk assessment showed there have been more than 500 cases on the French mainland, with cases also discovered in the UK and Germany.  More...

Long COVID patients lack naive T and B cells

Nature article: “Patients with long COVID had highly activated innate immune cells, lacked naive T and B cells and showed elevated expression of type I IFN (IFN-β) and type III IFN (IFN-λ1) that remained persistently high at 8 months after infection”

“T cell activation (indicated by CD38 and HLA-DR), T cell exhaustion and increases in B cell plasmablasts occur during severe COVID-19”

Full Nature article: Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

 

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Global case fatality rate drops to its lowest ever level during the pandemic

Finally, some good news on the Covid front. Whilst the world battles its way through a blizzard of Omicron, the lower death rate for the variant has sent the global case fatality rate tumbling to just 1.86%, the lowest level since the beginning of the pandemic.  More...