Category: E484K
New Philippines coronavirus variant has 484K and 501Y mutations
On Thursday, the Department of Health (DoH) in Central Visayas (The Philippines) confirmed that they have detected two mutations with “potential clinical significance” of SARS-CoV-2 that cause the disease. More...
Japan finds new coronavirus variant with 484K mutation in 91 patients
Japan has confirmed that a new variant of Sars-COV-2 with the E484K mutation on the spike protein has been found in 91 patients. More...
New coronavirus variant B.1.525 with E484K, Q677H, F888L and a similar deletions to B117
International lineage with variants of biological significance E484K, Q677H, F888L and a similar suite of deletions to B.1.1.7. More...
Kent Sars-Cov-2 variant with E484K mutation found in Bristol named VOC 202102/02
A mutated version of the coronavirus variant first detected in Kent has been classified as a cause for “concern” by scientific advisers to the government. More...
Brazil co-infection sees patients infected with two variants of coronavirus at the same time
“We were the first to identify two independent events of co-infection caused by the occurrence of B.1.1.28 (E484K) with either B.1.1.248 or B.1.91 lineages. More...
Reinfection from SARS-CoV-2 lineage P.2 with the E484K spike mutation in Brazil
We report the first case of reinfection from genetically distinct SARS-CoV-2 lineage [P.2] presenting the E484K spike mutation in Brazil, a variant associated with escape from neutralizing antibodies. More...
Brazilian researchers find patients infected with two different coronavirus strains
Researchers in southern Brazil said they have discovered patients infected with two different strains of the new coronavirus simultaneously, reflecting concerns about the growing number of variants in the country. More...
Sars-Cov-2 lab variant bound 600 times more successfully to human cells than the original strain
The naturally selected mutations S477N, E484K, and N501Y of the Spike protein RBD, which show higher infectivity, were selected by yeast surface display affinity maturation already in the first round, giving rise to the South-African, E484K, N501Y, and British variants that bind ACE2 13 and 3.5-fold tighter than RBD-WT. More...
Denmark finds 4 coronavirus cases which only have the E484K mutation in the spike protein
The first case of another covid-19 variant has been found in Denmark. More...
Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus, Brazil
“We have detected a new variant circulating in December in Manaus, Amazonas state, north Brazil, where very high attack rates have been estimated previously. More...