Category: B.1.1.7

Antibody resistance of coronavirus variants B.1.351 (SA) and B.1.1.7 (UK)

“Findings on B.1.351 [South Africa variant] are more worrisome in that this variant is not only refractory to neutralization by most NTD mAbs but also by multiple individual mAbs to the receptor-binding motif on RBD, largely owing to an E484K mutation.  More...

Coronaheadsup.com Africa, America, B.1.1.7, B.1.351, Brazil, Coronavirus, E484K, Europe, Health, Infection, K417N, Mutation, Reinfection, Science, South Africa, Testing, Transmission, Treatment, UK, Vaccine, Variants

New coronavirus variant in Oregon has B.1.1.7 backbone with E484K mutation – “seems to have evolved independently”

The new coronavirus variant that surfaced in Oregon has the same B.1.1.7 backbone, but also a mutation – E484K, or “Eek” – seen in variants of the virus circulating in South Africa, Brazil and New York City.  More...

Coronaheadsup.com America, B.1.1.7, Coronavirus, E484K, Health, Infection, Mutation, Oregon, Testing, USA, Vaccine, Variants

B.1.1.7 coronavirus variant infections have the potential to cause substantial additional mortality

The mortality hazard ratio associated with infection with VOC-202012/1 [B.1.1.7] compared to infection with previously circulating variants is 1.64 in patients who have tested positive for COVID-19 in the community.  More...

Coronaheadsup.com B.1.1.7, Coronavirus, England, Europe, Health, Infection, Lockdown, Mutation, Northern Ireland, Science, Scotland, Testing, UK, Vaccine, Variants, Wales