Tag: B.1.1.7

Oxford University: “vaccine effective against major B.1.1.7 ‘Kent’ coronavirus strain circulating in the UK”

“Data from our trials of the ChAdOx1 vaccine in the United Kingdom indicate that the vaccine not only protects against the original pandemic virus, but also protects against the novel variant, B.1.1.7”

The Oxford University researchers who developed the ChAdOx1-nCoV 19 vaccine have found that it remains effective against one of the new variants of the disease.  More...

Coronaheadsup.com Astrazeneca, B.1.1.7, Coronavirus, England, Europe, Health, Infection, Mutation, Science, UK, Vaccine, Variants

Circulating SARS-CoV-2 variants B.1.1.7, 501Y.V2, and P.1 have gained ability to utilize rat and mouse Ace2 and altered in vitro sensitivity to neutralizing antibodies and ACE2-Ig

Here, we first investigated cross-species receptor usage of multiple SARS-CoV-2 variants that emerged during the pandemic.  More...

Coronaheadsup.com Africa, America, Animals, B.1.1.7, B.1.351, Brazil, Coronavirus, England, Europe, Health, Infection, Mutation, N501Y, P.1, Reinfection, Science, Scotland, South Africa, UK, Vaccine, Variants, Wales

Sars-Cov-2 lab variant bound 600 times more successfully to human cells than the original strain

The naturally selected mutations S477N, E484K, and N501Y of the Spike protein RBD, which show higher infectivity, were selected by yeast surface display affinity maturation already in the first round, giving rise to the South-African, E484K, N501Y, and British variants that bind ACE2 13 and 3.5-fold tighter than RBD-WT.  More...

Coronaheadsup.com Coronavirus, E484K, Health, Infection, Mutation, N501Y, Reinfection, Science, Treatment, Vaccine