Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil P1 coronavirus

Through genome sequencing of viruses sampled in Manaus between November 2020 and January 2021, we identified the emergence and circulation of a novel SARS-CoV-2 variant of concern, lineage P.1, that acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor.  More...

Phylogenetic relationship of SARS-CoV-2 sequences from Amazonas with emerging Brazilian variants harboring mutations E484K and N501Y in the Spike protein

Here we report a preliminary genomic analysis of SARS-CoV-2 B.1.1.28 lineage circulating in the Brazilian Amazon region and their evolutionary relationship with emerging and potential emerging SARS-CoV-2 Brazilian variants harboring mutations in the RBD of Spike (S) protein.  More...

Oslo, Norway: new coronavirus lockdown closes restaurants, non-essential shops & secondary schools

In Oslo, all restaurants, except take-away services, and non-essential shops, except groceries, pharmacies and liquor stores, will have to close from Tuesday, while the “red” level is imposed at upper secondary schools, meaning that students, who were fully back at school, will now do some online learning.  More...